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MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer
Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The
New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by half. The results are presented today at the European Association of Urology Congress. Our results from a large, randomised study show that modern methods for prostate cancer screening maintain the benefits of screening, while decreasing the harms substantially. This addresses the greatest barrier to the introduction of nationwide screening, explains Tobias Nordström, associate professor of Urology at the Department of Clinical Sciences, Danderyd Hospital at Karolinska Institutet, who is in charge of the
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A by-product of nicotine, found in the urine of smokers, could be used to identify when bladder cancer has returned, new research has found.
The pilot study, presented today at the 2021 European Association of Urology Congress, found that patients with high levels of cotinine were four times more likely to have their cancer return, compared to those with lower levels of the chemical. The researchers goal is that a simple urine test for cotinine could reduce the number of invasive investigations that cancer patients undergo following diagnosis and treatment.
Cotinine is a chemical that is made by the body from nicotine, which acts as a marker for exposure to tobacco smoke. Smoking is a major risk factor for bladder cancer, but this is the first study to show how cotinine levels could be used to signal recurrence of the disease.
MRI can cut overdiagnoses in prostate-cancer screening by half eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.