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Experts explore new frontiers for AI in cancer care
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Seagen (SGEN) Announces Long-Term Results from TUKYSA Pivotal Trial in Patients with HER2-Positive Breast Cancer During ASCO
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- Updated Analysis Shows Median Overall Survival for TUKYSA Arm Extended to Two Years, with Benefit Maintained Across All Prespecified Patient Subgroups in HER2CLIMB Trial -
- Results Further Support TUKYSA as Well-Tolerated Treatment Option That Improves Survival in Patients with Previously Treated Metastatic HER2-Positive Breast Cancer With and Without Brain Metastases - Seagen Inc. (Nasdaq:SGEN) today announced that improvements in overall survival (OS) and progression-free survival (PFS) were maintained with long-term follow up from the pivotal HER2CLIMB trial evaluating the addition of TUKYSA (tucatinib) to trastuzumab and capecitabine in patients with HER2-positive metastatic breast cancer (MBC) with and without brain metastases. Data from the pre-specified exploratory analysis will be presented (Abstract #1043) as part of the virtual scientific program of the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting.
A cancer patient in Louisville, Kentucky, receives a dose of a coronavirus vaccine.
PHOTO: JON CHERRY/GETTY IMAGES
For Eva Schrezenmeier, a nephrologist at Charité University Hospital in Berlin, the news was sobering: Among 40 patients with transplanted kidneys at her hospital who d been vaccinated against COVID-19, only one was churning out the antibodies that would likely protect him from the disease. Because transplant patients take powerful drugs to suppress the immune system so it doesn t attack a donated organ, her team expected diminished responses to a vaccine. But Schrezenmeier, who posted a preprint describing her study last week, hadn t anticipated just how badly the vaccine might falter in her patients.
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