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HIV vaccine efforts are undermined by off-target antibodies ANI 29 Jul 2021, 13:37 GMT+10 California [US], July 29 (ANI): Some proof-of-concept HIV vaccines in early human trials generate antibodies that actively hinder protection by degrading the vaccine s payload, suggests a new study from Scripps Research. Their study was published in the journal Science Advances. While scientists have had rapid success engineering vaccines against the pandemic coronavirus in less than a year s time, HIV, the virus responsible for the AIDS epidemic, has proven significantly more challenging. Understanding how off-target antibodies may be undermining HIV vaccine prototypes allows for design improvements, says the study s lead author, Andrew Ward, PhD, a structural biology professor at Scripps Research in La Jolla, CA.

United statesLars hangartnerHannah turnerDennis burtonAndrew wardScripps researchUnited nations programNational institutes of healthScripps research in la jollaDepartment of immunologyImmunodeficiency virusNational institutesJoint united nations programஒன்றுபட்டது மாநிலங்களில்ஹன்னா டர்னர்டென்னிஸ் பர்டன்