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Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy. The body s immune system is a critical defense against illness such as infections, as has been highlighted by the recent COVID-19 pandemic. The same immune system can also help us fight cancer. However, pancreatic cancer is different; a key feature of this cancer type is that the pancreatic cancer cells are surrounded by a dense, impenetrable barrier known as the stroma, which often blocks the access of immune cells to the tumor. For this reason, immunotherapies - drugs that harness the power of the body s immune system to kill cancer cells - have shown limited success in the treatment of pancreatic cancer,

Immune cells can be stimulated to boost effects of chemotherapy in pancreatic cancer: Study

Immune cells can be stimulated to boost effects of chemotherapy in pancreatic cancer: Study ANI | Updated: Jul 10, 2021 10:32 IST Washington [US], July 10 (ANI): A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer, such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy. The research was published in Cellular and Molecular Gastroenterology and Hepatology, and funded by Cancer Research UK, Pancreatic Cancer Research Fund and Medical Research Council. The body s immune system is a critical defense against illnesses such as infections, as has been highlighted by the recent COVID-19 pandemic. The same immune system can also help us fight cancer.

UK Tissue Bank Open for Pancreatic Research

Jan 07 2021 Read 271 Times UK-based researchers needing samples of blood, urine and saliva to aid their pancreatic diseases research can now turn to the Pancreatic Cancer Research Fund Tissue Bank (PCRF Tissue Bank), created to help drive the development of diagnostic tools and new treatments in this field. Set up in 2016 with £2.4 million from the medical research charity and coordinated from the Barts Cancer Institute at Queen Mary University of London, the PCRF Tissue Bank is the largest of its kind in the world and now holds some 45,000 unique samples of blood, urine, saliva and tissue as well as matched surrounding healthy tissue, donated from 2,200 consenting patients (collected over 2,800 visits) who underwent biopsies or surgery for a range of pancreatic diseases at one of eight partner hospitals across the UK. 

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