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 E-Mail IMAGE: The scientists found elevated levels of cell drinking, or macropinocytosis (green) in the stromal cells exposed to a low-nutrient environment (right), compared to normal nutrient levels that surround healthy tissue. view more  Credit: Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking cell drinking, or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth providing more evidence that macropinocytosis is a driver of pancreatic cancer growth and is an important therapeutic target. The study was published in Now that we know that macropinocytosis is revved up in both pancreatic cancer cells and the surrounding fibrotic tissue, blocking the process might provide a double whammy to pancreatic tumors, says Cosimo Commisso, Ph.D., associate professor and co-director of the Cell and Molecular Biology of C

United statesSan diegoAndrewm lowyDavida scottKoenmo galenkampCosimo commissoOlga zagnitkoLynn matrisianYijuan zhangMichael jungYunbo liSanford burnham prebysUniversity of californiaAmerican association for cancer researchNational institutes of healthPancreatic cancer action network pan