UNION therapeutics COVID-19 candidates found to be well tolerated in Phase 1 Lancet publication
The Lancet Regional Health - Europe has published the results of UNION therapeutics phase 1 study of inhaled and intranasal niclosamide products (UNI91103 and UNI91104)
The study endpoints were to assess the safety profile and the pharmacokinetic profile of niclosamide when administered as a nasal spray and as an inhalation product (nebulizer)
The study was placebo-controlled and conducted in healthy volunteers
No adverse effects were identified, paving the way for further investigation in COVID-19 patients
On the basis of these results UNI91103 has been selected as the first intervention of the PROTECT-V study, which recently received UK Urgent Public Heath prioritization
New international platform will help increase supply for sustainable fuels for the marine market
A new ShippingLab project is going to create an internationally recognized platform for testing and validating new fuel solutions that can aid in significantly reducing or eliminating GHG emissions from the shipping industry. As such, the purpose of the platform is to assist the global transition towards sustainable marine fuels by creating a bridge between prospective suppliers of sustainable fuels and the marine industry.
Behind the validation platform there is a number of important stakeholders, namely Mærsk Mc-Kinney Møller Center for Zero Carbon Shipping, Alfa Laval, MAN Energy Solutions, DS Norden and A.P. Møller – Mærsk and the supplier of biofuel MASH Energy.
2 March 2021 15:26 GMT Updated 2 March 2021 15:27 GMT
It’s well-known within the wind power industry that as much as 90% of a turbine can be recycled. Less fully understood is that to achieve the much-sought after “100% recycling” milestone, we still need to find a sustainable after-life solution for the blades.
Blades are, in fact, 100% recyclable. There are already mature technologies that use blades as feedstock in cement co-processing, for instance, and the ‘granulates’ of recovered fibreglass and other materials put through mechanical grinding can be used for a range of new products.
However, being fully recyclable in theory doesn’t really matter, if the blades are not recycled in practice. And it is clear that the lack of large-scale, cost efficient recycling value chains for blades – which are made of polymer-rich composite materials – remains a significant hurdle.
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IMAGE: To describe the structure of properdin oligomers, the researchers used two independent techniques. In the panels with a dark background, the properdin molecule is seen as a light triangular molecule. view more
Credit: Dennis Vestergaard Pedersen and Gregers Rom Andersen
After seven years of intense research, a research group from Aarhus University has succeeded - through an interdisciplinary collaboration - in understanding why a very extended structure is important for an essential protein from the human immune system. The new results offer new opportunities for adjusting the activity of the immune system both up and down. Stimulation is interesting in relation to cancer treatment, while inhibition of the immune system is used in treatment of autoimmune diseases.