10 Aug 2021
Immune checkpoints are molecules that signal and control the synapse between T cells and antigen presenting cells (APCs). Checkpoint inhibitor therapies aim to target and inhibit the signals that ‘switch off’ T cells, leading to upregulation of T cell activation and tumor cell killing.
The mixed lymphocyte reaction (MLR) mimics the T cell and APC synapse by co-culturing immune cells from two individuals. Consequently, MLR is used as a model, to discover the effects of checkpoint inhibitor drugs in vitro, furthering biological research applications and drug discovery processes.
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The use of the iQue
Special Feature: 10 top new resources to advance your engineered antibody research
Explore our exclusive interviews, free downloads, latest methods, and much more to help support your antibody research
16 Mar 2021
As part of our new special feature, we’ve pulled together a selection of the top new resources to aid your work with engineered antibodies. Download our comprehensive guide to optimal antibody selection and application, discover the value of label-free technology for streamlined drug discovery workflows, explore the development of next-generation antibodies, and much more.
Transform your immunoassay: Choose the right antibody for you
In this interview, Dr. Christian Frisch, R&D manager at Bio-Rad Laboratories, explains how to design a reliable assay and reveals how Bio-Rad and Sartorius teamed up to help scientists achieve peak immunoassay performance.
Top resources to advance your engineered antibody research selectscience.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from selectscience.net Daily Mail and Mail on Sunday newspapers.
Expert Insight: Don t miss out on these 6 new expert webinars
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22 Feb 2021
SelectScience
® hosts dozens of informative and insightful free webinars for scientists every month, featuring world-class speakers at the very forefront of their respective fields. In our regular weekly feature, we ll be highlighting the exciting and informative events you won t want to miss over the next week or so, as well as some of our top on-demand webinars. Register now to save your spot and hear from experts as they discuss the latest research and technologies in their fields, from
in vitro diagnostics and advances in COVID-19 sample prep to neonatal hypocalcemia and cytotoxicity assay development.
Hear from Dr. Beatrice Marg-Haufe how Tecan’s Resolvex A200
® can be implemented quickly to significantly increase throughput for labor-intensive extraction procedures and how it’s an alternate, cost-effective solution for sample preparation using filter plates and positive pressure technology. This webinar is part of our COVID-19 series.
Tuesday, February 16, 16:00 GMT / 17:00 CET / 11:00 EST / 08:00 PST
CYTOTOXICITY ASSAYS: How to streamline the assay development of a cytotoxicity assay for high-content compound screening
In this webinar, Dr. Christopher Wolff, FMP Berlin, presents a fast and reliable method to develop a cytotoxicity assay for high-content screening using Tecan’s Spark
® Cyto multimode reader with imaging capabilities.