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Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.
The research, led by scientists at Children s Cancer Institute and published this week in the international journal,
Cell Reports, offers an exciting new therapeutic approach for the treatment of DIPG by using a new anti-cancer drug.
The new drug, CBL0137, is an anti-cancer compound developed from the antimalarial drug quinacrine. The researchers found that CBL0137 directly reverses the effects of the key genetic drivers in DIPG, and has a profound effect against DIPG tumour models. They also foundCBL0137 is even more effective when combined with a second drug, panobinostat, a new type of drug known as a histone deacetylase (HDAC) inhibitor. When used
Researchers find potential new treatment for fatal childhood brain cancer ANI | Updated: Feb 14, 2021 19:22 IST
Washington [US], February 14 (ANI): Every year around 20 Australian children die from the incurable brain tumour, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years. There are no effective treatments, and almost all children die from the disease, usually within one year of diagnosis.
A paper published in the journal Nature Communications, reveals a potential revolutionary drug combination that in animal studies and in world-first 3D models of the tumour is spectacularly effective in eradicating the cancer cells, according to lead researcher and paediatric oncologist Associate Professor c from the Children s Cancer Institute and Sydney Children s Hospital.
Updated: 10:09 AM CST Feb 5, 2021 KMBC 9 News Staff The Cure Starts Now announced Friday they have received a donation of $8,100 from the 15 and the Mahomies Foundation, the charity of Kansas City Chiefs quarterback, Patrick Mahomes.The donation is in honor of Whitney Wells, the courageous little girl who befriended Mahomes during her battle with diffuse intrinsic pontine glioma a highly aggressive and fast-growing form of brain cancer.Wells was diagnosed shortly after her 10th birthday in May 2019. Her relationship with Mahomes and other Chiefs players and staff began later that summer at Kansas City Chiefs training camp. There, she gave Mahomes her powder blue and light pink fundraising bracelet with “Whitney Wells” and “You got this!” written on it in baby pink. Mahomes wore the wristband all season long on his throwing arm en route to his Super Bowl LIV and MVP victories last season. He has continued to wear the baby pink wristband in honor of
January 14, 2021 · ·
Gold Star is proud to continue its tradition of giving back to the community in the midst of a challenging year.
Cincinnati, OH (
RestaurantNews.com) For over 55 years,
Gold Star Chili has been committed to service at every level: through business leadership and partnerships on both local and national levels that help make a difference in our communities. In the midst of a global pandemic and social and financial upheaval, the Gold Star family has stepped up to support longstanding partners, local charities, and the community at large.
Earlier this year, Gold Star launched our new #GivingTuesdayNow initiative, showing support to various nonprofits needing resources to serve our communities. Each week, Gold Star partnered with a select nonprofit organization to bring awareness to its mission, needs, and work being done in the community.
A Look Back at Gold Star Fundraising Initiatives in 2020
January 14, 2021 · ·
Gold Star is proud to continue its tradition of giving back to the community in the midst of a challenging year.
Cincinnati, OH (
Gold Star Chili has been committed to service at every level: through business leadership and partnerships on both local and national levels that help make a difference in our communities. In the midst of a global pandemic and social and financial upheaval, the Gold Star family has stepped up to support longstanding partners, local charities, and the community at large.
Earlier this year, Gold Star launched our new #GivingTuesdayNow initiative, showing support to various nonprofits needing resources to serve our communities. Each week, Gold Star partnered with a select nonprofit organization to bring awareness to its mission, needs, and work being done in the community.