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BLINCYTO® Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia

Amgen today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia were published in The Journal of the American Medical Association . 1 BLINCYTO … Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in The Journal of the American Medical Association (JAMA) . 1

Puerto ricoUnited statesNew zealandTrish rowlandJessica akopyanFranco locatelliDavidm reeseNational cancer instituteOperations center grantEuropean unionUniversity of romeDevelopment agreementNational clinical trials networkNational institutes of healthChildren oncology groupAdministration guidelines

BLINCYTO® (Blinatumomab) Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia

Share this article Share this article THOUSAND OAKS, Calif., March 2, 2021 /PRNewswire/ Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in The Journal of the American Medical Association (JAMA). 1 BLINCYTO demonstrated significantly prolonged event-free survival (events were defined by relapse, death, second malignancy, or failure to achieve complete remission) compared with chemotherapy. After a median of 22.4 months follow-up, 69% of patients treated with BLINCYTO were alive and event-free compared with 43% of patients treated with chemotherapy. Additionally, following treatment with BLINCYTO, 93% of patients with MRD at baseli

Puerto ricoUnited statesNew zealandTrish rowlandJessica akopyanFranco locatelliDavidm reeseNational cancer instituteOperations center grantEuropean unionUniversity of romeDevelopment agreementNational clinical trials networkNational institutes of healthChildren oncology groupAdministration guidelines

Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial | Pediatric Cancer | JAMA

Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial | Pediatric Cancer | JAMA
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SpringWorks Therapeutics Reports Fourth Quarter and Full Year 2020 Financial Results and Recent

Press release content from Globe Newswire. The AP news staff was not involved in its creation. SpringWorks Therapeutics Reports Fourth Quarter and Full Year 2020 Financial Results and Recent . SpringWorks Therapeutics, Inc.February 25, 2021 GMT - Reported Interim Data from Phase 2b ReNeu Trial of Mirdametinib in NF1-PN Demonstrating Encouraging Clinical Activity and Tolerability in the First 20 Adult Patients Enrolled - - - Continued to Strengthen Nirogacestat Patent Portfolio - - Multiple Data Readouts Expected in 2021 Across Pipeline, Including Topline Data from Phase 3 DeFi Trial in Desmoid Tumors and Initial Nirogacestat BCMA Combination Data - ADVERTISEMENT - Ended 2020 with $561.8 Million in Cash, Cash Equivalents and Marketable Securities -

United statesSouthwest finlandSaqib islamTatu pantsarChildren oncology groupJazz pharmaceuticalsDrug administrationUniversity of eastern finlandExchange commissionDevelopment rd expensesTrademark office for patent application noSpringworks therapeutics incInterim dataReneu trialEncouraging clinical activityPatients enrolled

Internationally Renowned Physician-Researcher Joins Phoenix Children s, University of Arizona College of Medicine

Share this article Share this article PHOENIX, Feb. 8, 2021 /PRNewswire/ In the culmination of a year-long, nationwide search, Phoenix Children s and the University of Arizona College of Medicine – Phoenix today announced the hire of Stewart Goldman, M.D., as chair of the Department of Child Health and senior vice president of research. Stewart Goldman, M.D. Dr. Goldman, who assumes his post on April 1, is an internationally renowned pediatric oncologist and physician-researcher whose appointment is part of a long-term, strategic effort to strengthen Phoenix Children s research program, bring bench-to-bedside treatments to the health system s patients and enhance its world-class clinical programs.

United statesLoyola university stritch school of medicineMemorial hospitalUniversity of arizonaUniversity of chicagoLoyola universityMichael kruerMeryl suzanne weissYoutube linkedin instagramAnn roberth lurieRobertl meyerDan ostlieJared muenzerMitch shubAmerican society for pediatric hematology oncologyAmerican society of clinical oncology