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Science s COVID-19 reporting is supported by the Heising-Simons Foundation
It s been one step forward, two back for AstraZeneca s COVID-19 vaccine. Even as the company rebutted criticism of its efficacy claims last week, a bigger problem loomed for the vaccine and the many millions depending on it. Evidence continues to accumulate that an unusual clotting disorder seen in dozens of European recipients is a real, albeit rare, side effect. A preprint has detailed a proposed mechanism, and multiple scientific groups have said the worry is legitimate and must be seriously weighed against the vaccine s COVID-19 protection.
This week, Canada and Germany joined Iceland, Sweden, Finland, and France in recommending against the vaccine s use in younger people, who seem to be at higher risk for the clotting problem and are less likely to develop severe COVID-19. The approach makes sense given that other vaccines are available, says Sandra Ciesek, a virologist at Goethe University Frankfurt.
Yves here. The media has focused on Covid developments, and in the US, the pitched battles over the stimulus package. What is widely acknowledged by those paying attention is that the European stimulus is way too small, and that was before the prospect of yet another set of lockdowns was in the offing. Italian banks were looking plenty wobbly even before Covid took hold, and they’ve long been seen as big enough to have the potential to set off a wider conflagration.
Given the serious and continuing costs of Covid, the EU’s budget short-sightedness will produce avoidable damage to businesses. That will blow back directly to banks, since unlike the US, most corporate financing comes from banks. Interestingly, the authors think a meltdown scenario is possible and recommend direct rescues of businesses over banks.
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Vaccination formula: rapid vaccination could avoid lockdown even with rising infection numbers
As it has from the beginning, the pandemic continues to primarily affect older people. If the entire population of Germany became infected with SARS-CoV-2, statistically 1.5 million of those over 60 would die; among those under 60, the death toll would “only” be 75,000. This is why – in addition to certain particularly exposed population groups – vaccination strategies often prioritise the elderly with the aim of avoiding overburdening the health system with severe COVID-19 cases and high death rates. After all, vaccinating just a quarter of the population can prevent 95 percent of deaths.
Side effect worry grows for AstraZeneca vaccine sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.