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SINGAPORE (Bloomberg/Reuters/AFP): The AstraZeneca Covid-19 vaccine came under the spotlight following reports of rare blood clots, some of them fatal, among some adult vaccine recipients.
Concerns about the vaccine centred on an unusual type of blood clot in the brain called cerebral venous sinus thrombosis (CVST). There were also some cases of clots in the abdomen and in the arteries, which occurred together with low levels of blood platelets.
The European Medicines Agency said it had reports of 169 cases of the rare clotting disorder out of 34 million doses administered within Europe, roughly one for every 100,000 people under 60 vaccinated. Most occurred in women under 55 and within two weeks of injection.
BERLIN/ZURICH (REUTERS) - Instances of a very rare clotting condition in women aged under 60 who received AstraZeneca s Covid-19 vaccine were 20 times higher than would normally be expected, Christian Bogdan, a member of Germany s vaccine committee, said on Wednesday (April 7).
The EMA conducted an in-depth review of 86 cases, including 18 fatalities.
In comparison, four women out of 10,000 would get a blood clot from taking oral contraception.
Bogdan did not specify how many cases of blood clots with low blood platelet counts would be expected in a normal population, but said their higher prevalence in one population group over a defined timeframe represented a very clear risk signal .
Two of the scientists behind Britain s AstraZeneca jab could both make £26million today as the tech firm that developed it hits the US stock market.
Oxford professors Sarah Gilbert and Adrian Hill both own 5.2 per cent of Vaccitech, which will later float on America s Nasdaq exchange.
The pair are alongside other scientists and investors who put money and expertise into the company after it was founded in 2016.
Companies House papers audited by MailOnline show Profs Gilbert and Hill each hold 2,500 ordinary shares in the firm, out of a total 47,827.
Experts have suggested it is targeting a value of some £509 million, meaning if this is realised, the two scientists stakes will be each worth £26.4million.
Government s vaccine advisory group recommended healthy people aged 19 to 29 offered different vaccine
Review by drugs watchdog MHRA found that 79 out of 20m Britons given AZ vaccine suffered blood clots
MHRA insisted there was still no concrete proof vaccine is causing the clots, but admitted link getting firmer
Matt Hancock said it showed the safety system is working because regulators can spot extremely rare event
He said AstraZeneca vaccine is safe and there is more than enough Moderna and Pfizer jabs for under-30s
Health Secretary also insisted Government remains on course to offer all UK adults a jab by the end of July