February 5, 2021 Multiparametric MRI-targeted biopsy for clinically significant prostate cancer can yield detection rates similar to systematic transrectal ultrasound-guided (TRUS) biopsy, while potentially enabling over one-third of prostate biopsies to be avoided, according to research published online February 4 in
In a multicenter, prospective, and randomized phase III study called PRostate Evaluation for Clinically Important Disease: MRI vs. Standard Evaluation Procedures (PRECISE), a team of researchers from Canada found that providing targeted biopsies after a positive multiparametric MRI scan was noninferior to systematic TRUS biopsies for detecting prostate cancers with an International Society of Urological Pathology grade group (GG) of 2 or higher.
COVID-19 vaccines are ‘ethically justified’ for pregnant, breastfeeding women, but shouldn’t be routinely offered
Commentary issued by the Canadian Medical Association Journal said a person s choice must be respected
(Stock)
Medical experts are saying pregnant and breastfeeding women should not be routinely offered COVID-19 vaccines until more data is gathered, but the same experts are saying it is ethically justified to offer the vaccines to those who want it.
The recommendation is part of a commentary recently published by the Canadian Medical Association Journal (CMAJ) and said vaccines can be considered in certain scenarios where the benefits are deemed to outweigh the risks.
Colin Perkel
A nurse places a pulse oximeter to measure the oxygen level and heart rate of a man who is recovering from pneumonia at his home, Thursday, July 9, 2020, in Ipswich, Mass. One saving grace amid the devastation of COVID-19 pandemic has been that the vast majority of those infected are able to recover at home, allowing hospitals to cope with what would otherwise have been a system-crushing onslaught of ill, contagious patients.THE CANADIAN PRESS/AP/Elise Amendola February 04, 2021 - 9:49 AM
TORONTO - One saving grace amid the devastation of COVID-19 has been that the vast majority of those infected are able to recover at home, allowing hospitals to cope with what would otherwise have been a system-crushing onslaught of ill, contagious patients.
Posted: Feb 04, 2021 6:00 AM AT | Last Updated: February 4
Toronto microbiologist Dr. Samira Mubareka was part of the first Canadian research team to successfully isolate SARS-CoV-2 and study its genetic code. The data is still coming in on the coronavirus variant, but evidence suggests it does spread more easily, she says.(Kevin van Paassen/Sunnybrook Health Sciences Centre)
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Prostate MRI followed by selective biopsy detected as many clinically significant cancers as standard ultrasound-guided systematic biopsy and detected 50% fewer low-risk cancers, a large randomized trial showed.
Targeted biopsy with multiparametric MRI identified grade group (GG) ≥2 tumors in 35% of men as compared with 30% for systematic biopsy with transrectal ultrasound (TRUS) guidance. The proportion of GG1 tumors decreased from 22% with TRUS biopsy (Bx) to 10% with targeted MRI-guided biopsy. Almost 40% of men randomized to the MRI group had negative imaging results, allowing them to avoid biopsy altogether.
Men who had MRI-guided prostate biopsy also had fewer adverse events (AEs), Laurence Klotz, MD, of the Sunnybrook Health Sciences Center in Toronto, and coauthors reported in