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IMAGE: A single mutation S10R with the replacement of serine at position 10 for arginine (highlighted in blue on the protein structure on the left), despite its removal from the chromophore. view more
Credit: Skoltech
Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS, and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure. The research was published in the
International Journal of Molecular Sciences.
An important research tool, phototoxic proteins are used as genetically encoded photosensitizers to generate reactive oxygen species under light irradiation. In contrast to common chemical photosensitizers, phototoxic proteins are genetically encoded and expressed by the cell itself, which makes them easy to control and direct to any selected compartment in the cell. Thanks to reactive oxygen
14 December, 2020
Allergies are becoming more common; this article, the fourth in a six-part series about the lymphatic system, explores the reasons for this and discusses what happens during allergic responses including anaphylaxis
Abstract
This article, the fourth in a six-part series on the lymphatic system, discusses the nature of allergy, exploring common allergens and the body’s response to them in atopic people, including anaphylaxis. It questions why allergies are becoming increasingly common, particularly in developed countries, exploring a number of theories.
Citation: Knight J, Nigam Y (2021) The lymphatic system 4: allergies, anaphylaxis and anaphylactic shock.
Nursing Times [online]; 117: 1, 54-58.
Authors: John Knight is associate professor in biomedical science; Yamni Nigam is professor in biomedical science; both at the College of Human and Health Sciences, Swansea University.
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