WKSU
After nearly 30 years with the Akron Public school system, Superintendent David James gives his last State of the Schools Address ahead of his planned retirement this summer. James highlights one of the school district s achievements, the College and Career Academies of Akron, during his address.
Akron Public Schools Superintendent David James delivered his final state of the schools address Thursday. James will retire this summer after 13 years as superintendent and 29 years with the district.
James has led an innovative effort to adopt the College and Career academies model for Akron schools. He noted the district recently received a $1.5 million grant from the Chan Zuckerberg Foundation that will help the district build opportunities through the academies.
Image by NIH
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune systemâs virus-fighting response just when they need it most, according to new UC San Francisco research published in
Nature.Â
Scientists believe this overzealous antibody response is an inappropriate engagement of an ancient biological feedback circuit whose real function is to help the body tamp down levels of immune signaling molecules called interferons, to modulate the immune response once a viral infection is under control. Â
Interferons help to stop a cellâs protein-making machinery, so viruses canât hijack it to make copies of themselves. But in patients with severe COVID-19, antibodies that block the effects of interferons appear prematurely, removing the cellsâ defenses while the infection is still raging.Â
Severe COVID-19 Disables Disease-Fighting Immune Circuit
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune system’s virus-fighting response just when they need it most, according to new UC San Francisco research published in
Nature.
Scientists believe this overzealous antibody response is an inappropriate engagement of an ancient biological feedback circuit whose real function is to help the body tamp down levels of immune signaling molecules called interferons, to modulate the immune response once a viral infection is under control.
Interferons help to stop a cell’s protein-making machinery, so viruses can’t hijack it to make copies of themselves. But in patients with severe COVID-19, antibodies that block the effects of interferons appear prematurely, removing the cells’ defenses while the infection is still raging.
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