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Initiated clinical trial with novel nasal spray codenamed APR-AOS2020 [ ]

12 maggio 2021 16:52 Fonte: Adnkronos #salute-e-benessere Product recently cleared in EU as Class III medical device BALERNA, Switzerland, May 12, 2021 /PRNewswire/ APR Applied Pharma Research s.a. (APR), a leader in the development of pharmaceutical drug delivery technologies and systems and innovative products derived thereof, today announced the start of a pivotal clinical trial to assess the efficacy of its product temporarily codenamed APR-AOS2020, a Class III medical device, in the treatment of COVID-19 patients showing mild symptoms. The study is being conducted by the Hygiene Unit of IRCCS Policlinico San Martino Hospital in Genoa, Italy and coordinated by Prof. Giancarlo Icardi as lead investigator. The study is planned to enroll a total of 57 COVID-19 patients who show mild symptoms of the disease and is evaluating the efficacy and safety of the spray product in reducing viral load in the upper respiratory airways in recently infected individuals. Results, when availa

Giving Cristiano Ronaldo an early Covid vaccination would convince sceptics, says Italian health official

A health official in Italy has suggested that Serie A footballers should be among the first in the country to be vaccinated against coronavirus, pointing specifically to the positive influence that could come from Cristiano Ronaldo receiving a jab. Professor Matteo Bassetti, a virologist and director of the Infectious Diseases Clinic at the San Martino Hospital in Genoa, wrote in an Instagram post that there could be numerous benefits to such a.

Dependence on Pain Meds and Sedatives Common After Breast Cancer Surgery

December 13, 2020 The risk of becoming dependent on pain medication and sedatives after mastectomy and breast reconstruction surgery is more significant than doctors realized.  A study presented this week at the virtual meeting of the San Antonio Breast Cancer Symposium (SABCS) found that people who underwent mastectomy and breast reconstruction were at increased risk of developing dependence on pain and sedative medication. The study showed that 13.1 percent of patients who were not prior opioid users became new persistent opioid users after surgery. Researchers found 6.6 percent of patients who were not prior sedative-hypnotic users became persistent users after surgery. “It’s striking how many patients this is an issue for. It’s more than maybe we would have thought prior to doing the study,” said the lead author, Jacob Cogan, MD, a fellow in hematology-oncology at NewYork-Presbyterian Columbia University Irving Medical Center in New York City.

SABCS: Pregnancy Less Likely After Breast Cancer Diagnosis

Dec 15, 2020 MONDAY, Dec. 14, 2020 (HealthDay News) Pregnancy is less likely after prior breast cancer (BC) diagnosis, according to the results of a review presented at the annual San Antonio Breast Cancer Symposium, held virtually from Dec. 8 to 11 . Eva Blondeaux, M.D., from IRCCS Policlinico San Martino Hospital in Genova, Italy, and colleagues conducted a systematic literature review to examine pregnancy after BC, fetal and obstetrical outcomes, disease-free survival (DFS), and overall survival (OS). Data were included from 39 studies with 57,739 women with cancers other than BC and 114,573 women with BC. The researchers found that 7,505 of the BC patients had a pregnancy after BC diagnosis. BC patients had lower chances of having a pregnancy following anticancer treatment completion compared to women from the general population (relative risk, 0.40). BC survivors had significantly increased risks of low birth weight, small for gestational age, preterm delivery, and cesarea

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