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COVID-19 virus triggers antibodies from previous coronavirus infections: Study

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease. Image/Dr. Fred Murphy & Sylvia Whitfield/CDC COVID-19 isn’t humanity’s first encounter with a coronavirus, so named because of the corona, or crown-like, protein spikes on their surface. Before SARS-CoV-2 the virus that causes COVID-19 humans have navigated at least 6 other types of coronaviruses. The study sought to understand how coronaviruses (CoVs) ignite the human immune system and conduct a deeper dive on the inner workings of the antibody response. The published findings, “Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses,” appear  in the journal

Tracking cancer metastasis with CRISPR opens new areas for drug development

Jan 22, 2021 8:52am Using CRISPR gene-editing technology, scientists were able to map out phylogenetic trees that track the lineage of individual cancer cells as they proliferate and metastasize. (Jeffrey Quinn/Whitehead Institute) Metastasis is responsible for most cancer-related deaths, but it’s hard to trace. Now, a group of researchers has developed a CRISPR-based method that helped track tumor spreading patterns. Researchers from the Massachusetts Institute of Technology (MIT), the University of California, Berkeley and the University of California, San Francisco used the CRISPR gene editing tool to map out a detailed family tree that revealed the dynamics behind the development and progression of cancer metastases.

Study results show COVID-19 virus triggers antibodies from previous coronavirus infections

 E-Mail The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease. COVID-19 isn t humanity s first encounter with a coronavirus, so named because of the corona, or crown-like, protein spikes on their surface. Before SARS-CoV-2 the virus that causes COVID-19 humans have navigated at least 6 other types of coronaviruses. The study sought to understand how coronaviruses (CoVs) ignite the human immune system and conduct a deeper dive on the inner workings of the antibody response. The published findings, Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses, appear today in the journal Cell Reports Medicine.

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