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With a name like glucose-6-phosphate dehydrogenase deficiency, one would think it is a rare and obscure medical condition, but that s far from the truth. Roughly 400 million people worldwide live with potential of blood disorders due to the enzyme deficiency. While some people are asymptomatic, others suffer from jaundice, ruptured red blood cells and, in the worst cases, kidney failure.
Now, a team led by researchers at the Department of Energy s SLAC National Accelerator Laboratory have uncovered the elusive mechanism behind the most severe cases of the disease: a broken chain of amino acids that warps the shape of the condition s namesake protein, G6PD. The team, led by SLAC Professor Soichi Wakatsuki, report their findings January 18th in
Algernon Highlights New Independent Research Review Identifying Ifenprodil as a Potential COVID-19 Treatment
Algernon Pharmaceuticals Inc. a clinical stage pharmaceutical development company, is pleased to highlight an independent research review published in the January 5 th edition of the European Archives of Psychiatry and Clinical Neuroscience that identified Ifenprodil as a possible re-purposed drug candidate for the treatment of COVID-19. The Review focuses on the sigma-1 receptor in the endoplasmic reticulum, a …
Algernon Pharmaceuticals Inc. (CSE: AGN) (FRANKFURT: AGW) (OTCQB: AGNPF) (the “ Company ” or “ Algernon ”) a clinical stage pharmaceutical development company, is pleased to highlight an independent research review (the “Review”) published in the January 5 th edition of the European Archives of Psychiatry and Clinical Neuroscience that identified Ifenprodil as a possible re-purposed drug candidate for the treatment of COVID-19.
Credit: Masami Hasegawa
In a study spanning four decades, researchers from the University of Hong Kong s Research Division for Ecology & Biodiversity (HKU) in the Faculty of Science, and Toho University s Department of Biology (Toho), Japan, have discovered that predation by snakes is pushing lizards to be active at warmer body temperatures on islands where snakes are present, in comparison to islands free from snakes. Their work also detected significant climatic warming throughout the years and found lizard body temperatures to have also increased accordingly. The findings show that lizard thermal biology is highly dependent on predation pressures and that body temperatures are rising suggest that such ectothermic predator-prey relationships may be changing under climatic warming.
Economic impact of the first wave of the COVID-19 pandemic on acute care hospitals in Japan Roles Conceptualization, Investigation, Validation, Writing – review & editing
Affiliations Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Pharmacy, National Center for Child Health and Development Hospital, Tokyo, Japan ⨯
Emi Teraoka, Roles Conceptualization, Investigation, Validation, Writing – review & editing
Affiliation Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Kyoto, Japan ⨯
Takuya Okuno, Roles Conceptualization, Investigation, Validation, Writing – review & editing
Affiliation Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Kyoto, Japan