Janssens’ COVID-19 vaccine effective against SARS-CoV-2 Delta variant
Researchers in the Netherlands have conducted a study showing that Janssen’s Ad26.COV2.S coronavirus disease 2019 (COVID‐19) vaccine was effective against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among eight individuals.
However, while all variants of concern tested were susceptible to vaccine-induced neutralizing activity, the effect was reduced compared with that observed for the first variant of SARS CoV-2 (B.1 lineage).
Compared with vaccine-induced neutralizing activity against the B.1 virus, the reduction in neutralization was greater for the B.1.351 (Beta) and P.1 (Gamma) variants than that observed for the rapidly spreading B.1.617.2 (Delta) variant.
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