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DRESDEN, Germany, Jan. 7, 2021 /PRNewswire/
GEMoaB, a biopharmaceutical company focused on the development of next-generation immunotherapies for hard-to- treat cancers, today announced the acceptance of two presentations on clinical data from the ongoing Phase I study of their lead asset UniCAR-T-CD123 in relapsed/refractory acute myeloid leukemia (rrAML) at the 2021 EHA-EBMT 3rd European CAR T-Cell Meeting, being held from February 4-6.
So far, CAR-T cell therapy in AML has been impacted by the lack of antigens differentially expressed on malignant blasts. Targeting CD123, which is also expressed on hematopoietic progenitor cells, with conventional CAR-T products has led to promising response rates but also to long-lasting aplasias, with the frequent need for subsequent allogeneic hematopoietic cell transplantation.
Image: Unsplash.
There’s no stopping the automation of vehicle functions. OEMs’ technologies might not be progressing by leaps and bounds, but they are still evolving at a rapid pace. Not a week goes by when we don’t hear about things like new sensors, new players like Apple Car, or Zoox’s vision of autonomous vehicles.
Automation is still a far cry from autonomy. Vehicles of different automation levels are already on our roads, taking care of an impressive array of features – and they’re here to stay. Sooner or later, however, autonomous vehicles will begin impacting our lives in the same way as the original automobile has since the late 19
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Hoppy beers such as pale ales are becoming increasingly popular. One reason is their pleasant fruity aroma that partially stems from compounds called thiols. Brewers have been looking for an accurate way to track thiols in beer, but current methods typically are not sensitive enough or require use of potentially harmful substances. Now, researchers in ACS
Journal of Agricultural and Food Chemistry present an automated, solvent-less process to assess thiols at very low concentrations.
Thiols, along with other compounds such as terpenes and esters, contribute to the enjoyable odors in hop-forward beer styles. Although very small amounts of thiols are present in beer, a little bit of these compounds goes a long way toward achieving a hoppy flavor and fruity aroma. Brewers would like more information about these volatile substances, but it s challenging to accurately detect such small quantities. Previous studies have reported complex, multi-step methods for thiol analysi
ISLAMABAD: National Assembly Standing Committee on Overseas Pakistanis and Human Resource Development on Wednesday refused to buy the ministry’s claim that the United Arab Emirates (UAE) has not imposed a ban on Pakistani workforce.
Moreover, as more overseas Pakistanis have returned home than those who have gone abroad, committee directed the ministry to take steps aimed at sending them back to overseas or adjust them in jobs within the country.
The committee, chaired by PML-N Sheikh Fayyazud Din, was held in a committee room of the Parliament House. Agenda of the meeting was to discuss the sufferings of the overseas Pakistanis due to Covid-19.