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Imaging helps understand empathy loss in dementia
A patient with frontotemporal dementia discovers his grandson’s birthday cake in the fridge. He doesn’t think twice before getting out a knife and fork and eating every last piece an hour before the birthday party is set to begin.
For patients with this early-onset neurodegenerative disease, some of the first symptoms are a profound loss of inhibition and empathy, which leads to a change in social behaviour that is completely out of character.
“He wasn’t thinking about his grandson at all; and typically, that loss of empathy extends even for those things where empathy is usually most robust, for example toward pets or grandchildren,” said Dr. Elizabeth Finger, associate professor at Western University’s Schulich School of Medicine & Dentistry and a neurologist at St. Joseph’s Health Care London.
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Canadian researchers are the first to study how different patterns in the way older adults walk could more accurately diagnose different types of dementia and identify Alzheimer s disease.
A new study by a Canadian research team, led by London researchers from Lawson Health Research Institute and Western University, evaluated the walking patterns and brain function of 500 participants currently enrolled in clinical trials. Their findings are published today in
Alzheimer s & Dementia: The Journal of the Alzheimer s Association. We have longstanding evidence showing that cognitive problems, such as poor memory and executive dysfunction, can be predictors of dementia. Now, we re seeing that motor performance, specifically the way you walk, can help diagnose different types of neurodegenerative conditions, says Dr. Manuel Montero-Odasso, Scientist at Lawson and Professor at Western s Schulich School of Medicine & Dentistry.
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