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Novel PET tracer is safe and can clearly identify early stages of rheumatoid arthritis

Novel PET tracer is safe and can clearly identify early stages of rheumatoid arthritis New research shows that a novel positron emission tomography (PET) tracer that targets inflammation is safe and can clearly identify early stages of rheumatoid arthritis. The promising PET tracer, 68Ga-DOTA-Siglec-9, rapidly clears from blood circulation, has a low radiation dose, and can be easily produced. This first-in-human study was published in the April issue of the Journal of Nuclear Medicine. Inflammation is a significant part of several chronic diseases, including rheumatoid arthritis and its related issues. While PET imaging with 18F-FDG is a valuable tool for the diagnosis and monitoring of the effects of treatments, it is not specific enough to assess inflammation.

Anne roivainenEmily hendersonJournal of nuclear medicineDrug researchUniversity of turkuTurku university hospitalPreclinical imagingRheumatoid arthritisMolecular imagingNuclear medicinePositron emission tomographyஎமிலி ஹென்டர்சன்இதழ் ஆஃப் அணு மருந்துமருந்து ஆராய்ச்சிபல்கலைக்கழகம் ஆஃப் டர்குடர்கு பல்கலைக்கழகம் மருத்துவமனை

Novel PET radiopharmaceutical shows promising results in first-in-humans study

Novel PET radiopharmaceutical shows promising results in first-in-humans study The preliminary trial results of a novel radiopharmaceutical for PET imaging of inflammation developed at the University of Turku, Finland, have been published. The compound, which targets the vascular adhesion protein 1 (VAP-1) that regulates inflammatory cell traffic, is the first radiopharmaceutical that has been developed completely in Finland and has advanced to clinical trials. In the study that started with healthy volunteers, the radiopharmaceutical was found to be well tolerated and safe. The radiopharmaceutical is 68Ga-labelled Siglec-9 peptide. The dose of the radiopharmaceutical used in PET imaging is thousands of times lower when compared with the regular drugs. Studies with new radiopharmaceuticals are therefore safer than the usual drug research studies.

Sirpa jalkanenOlli moisioRiikka viitanenAnne roivainenEmily hendersonAkademi universityUniversity of turkuTurku university hospitalProfessor anne roivainenRheumatoid arthritisஎமிலி ஹென்டர்சன்பல்கலைக்கழகம் ஆஃப் டர்குடர்கு பல்கலைக்கழகம் மருத்துவமனை

Promising results from first-in-humans study of a novel PET radiopharmaceutical

E-Mail IMAGE: The inflamed joints of a rheumatoid arthritis patient are clearly visible in the PET images with the novel 68Ga-DOTA-Siglec-9 radiopharmaceutical. view more Credit: Anne Roivainen The preliminary trial results of a novel radiopharmaceutical for PET imaging of inflammation developed at the University of Turku, Finland, have been published. The compound, which targets the vascular adhesion protein 1 (VAP-1) that regulates inflammatory cell traffic, is the first radiopharmaceutical that has been developed completely in Finland and has advanced to clinical trials. In the study that started with healthy volunteers, the radiopharmaceutical was found to be well tolerated and safe. The radiopharmaceutical is 68Ga-labelled Siglec-9 peptide.

Southwest finlandSirpa jalkanenOlli moisioRiikka viitanenAnne roivainenAkademi universityFinnish foundation for cardiovascular researchUniversity of turkuAcademy of finlandFinnish cultural foundationTurku university hospitalAatos erkko foundationResearchers riikka viitanenProfessor anne roivainenHospital districtSigrid jus

Turun vaihto-opiskelijoiden koronarypäs rauhoittumassa – tiukat rajoitustoimet tehonneet

Turun vaihto-opiskelijoiden koronarypäs rauhoittumassa – tiukat rajoitustoimet tehonneet
yle.fi - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from yle.fi Daily Mail and Mail on Sunday newspapers.

Southwest finlandTurku university of applied sciencesFinland turku universityTurku university hospitalJutta arable peninsula turku cityAddition southwest finlandArable peninsulaHer viewTurku universityApplied sciencesதென்மேற்கு பின்லாந்துடர்கு பல்கலைக்கழகம் ஆஃப் பயன்படுத்தப்பட்டது அறிவியல்டர்கு பல்கலைக்கழகம் மருத்துவமனைஅவள் பார்வைடர்கு பல்கலைக்கழகம்பயன்படுத்தப்பட்டது அறிவியல்

Turussa 37 uutta koronatartuntaa – maskipakko voimaan busseissa - Turun seutu

Turussa 37 uutta koronatartuntaa – maskipakko voimaan busseissa - Turun seutu
is.fi - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from is.fi Daily Mail and Mail on Sunday newspapers.

Southwest finlandFolin lauriTurku university hospitalTurku newMonday newMonday turkuCash in handTurku messagesதென்மேற்கு பின்லாந்துடர்கு பல்கலைக்கழகம் மருத்துவமனைதிங்கட்கிழமை புதியதுபணம் இல் கை