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Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients By 2030, pancreatic ductal adenocarcinoma (PDAC), the most lethal form of pancreatic cancer, is projected to become the second leading cause of cancer-related deaths in the United States. Not only are therapeutic options limited, but nearly half of all PDAC patients who have their tumors removed surgically experience disease recurrence within a year, despite receiving additional chemotherapy. For more advanced stages, only about one-third of patients have a limited response to approved chemotherapy. A team of researchers led by Dartmouth and Dartmouth-Hitchcock s Norris Cotton Cancer Center (NCCC) Director Steven D. Leach, MD, and Surajit Dhara, PhD, Senior Research Scientist in the Leach laboratory, in collaboration with colleagues at Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, are developing the first prognostic and therapeutic epigenetic biomarker

COVID-19 in New Hampshire: Updates about cases, variants, vaccinations

COVID-19 in New Hampshire: Updates about cases, variants, vaccinations © WMUR COVID-19 in New Hampshire Get the latest information below about the COVID-19 pandemic and its effects on New Hampshire. This page is updated daily. ^^ In the video player above, see the most recent COVID-19 briefing (from May 18, 2021) ^^Sign up for our Newsletters New Hampshire data: 7-day total test positivity rate (PCR & antigen): 2.5% Number of deaths attributed to COVID-19: 1,344 Number of active cases: 513 Number of patients who have recovered: 96,446 Number of current hospitalizations: 54 Total individuals fully vaccinated: 625,266 (46.1% of NH population) Number of B.1.1.7 variant (UK) cases: 728 Number of P.1 variant (Brazil) cases: 70

7-day average for daily new COVID-19 cases in NH down 68% in one month

7-day average for daily new COVID-19 cases in NH down 68% in one month Fewest active cases since Sept. 30 Share Updated: 7:17 PM EDT May 24, 2021 Fewest active cases since Sept. 30 Share Updated: 7:17 PM EDT May 24, 2021 Hide Transcript Show Transcript ASYMPTOMATIC INFECTION. IN NEW HAMPSHIRE, THERE ARE 52 NEW CASES OF COVID-19, THE FEWEST SINCE OCTOBER 4. IT IS VERY REASSURING WE ARE SEEING THIS DECLINE. KRISTEN: ACTIVE CASES HAVE ALSO DROPPED TO 411, THE FEWEST SINCE SEPTEMBER 30. CURRENT CASES ARE DOWN 87% IN THE LAST MONTH. WE MAY BE SEEING A TREND FOR IMPROVEMENT BECAUSE WE ARE ABLE TO DO THINGS OUTDOORS NOW. AS WE GO BACK INTO THE FALL AND WINTER, WE WOULD NOT WANT TO SEE ANOTHER SURGE BY US NOT BEING CAUTIOUS. KRISTEN: TO HELP PREVENT A SPIKE, DOCTORS ARE URGING PEOPLE TO GET VACCINATED TO PROTECT AGAINST SEVERE INFECTIONS, HOSPITALIZATIONS AND DEATH. I THINK WE DID A GOOD JOB, PARTICULARLY WITH HIGHER RISK PEOPLE. THAT IS EVIDENT, W

Valley News - Strafford woman navigates cancer, chronic pain as the opioid crisis complicates treatment

Strafford woman navigates cancer, chronic pain as the opioid crisis complicates treatment Katrina Short, of Strafford, Vt., has suffered from chronic pain since 1990 when she was injured while working as a nurse’s aid at a nursing home, and it has intensified over the past year as a result of spinal injuries, osteoporosis and lung cancer. After trying to help her husband David Short, left, make breakfast, she braces against the pain and nausea that prevent her from eating the meal on Friday, May 7, 2021. “I’ve always been a goer, a doer, and it really works on you mentally - not being able to do anything,” she said. “I’d really like to live a life off the couch.” (Valley News - James M. Patterson) Copyright Valley News. May not be reprinted or used online without permission. Send requests to permission@vnews.com.

Plainfield drops mask ordinance; Lebanon to hold public hearing

WEST LEBANON The Plainfield Selectboard voted to drop its mask mandate on Wednesday night, and Lebanon moved one step closer to rescinding its own as the City Council decided to schedule a public hearing on its ordinance.Lebanon councilors voted.

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