Mount Sinai
The Tisch Cancer Institute at Mount Sinai has been awarded a $1.9 million grant by the National Cancer Institute for an innovative study that will explore the mechanisms that enable tumor cells to spread from their original site but remain dormant for some time before becoming metastatic and threatening the lives of patients.
Jose Javier Bravo-Cordero, PhD, Assistant Professor of Medicine (Hematology and Medical Oncology) at the Icahn School of Medicine at Mount Sinai, and Scientific Advisor in the Advanced Bioimaging Center at The Tisch Cancer Institute, is the Principal Investigator for this five-year award.
Metastasis cancer that has spread from its original site to grow in other parts of the body is the main cause of death among patients with cancer, but the mechanisms involved in this phenomenon are unclear. Disseminated tumor cells, cells that have left the primary tumor and successfully seeded secondary target organs but have not yet formed tumors, have been rec
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New York, NY (December 17, 2020) Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?
The answer involves a protein called fas, and regulating fas may be a route to preventing cancer relapse, the researchers reported in a study published in
Cancer Discovery in December.
Cancer immunotherapies target antigens, or proteins, on the surface of tumor cells. One common example is a protein called CD19. But even when most cells in a tumor express CD19 on their surface, some do not. And tumors are constantly evolving and often experience antigen escape, meaning that the target is no longer expressed, which can make the immunotherapy fail and the cancer relapse.
Wheels Up Founder and CEO Kenny Dichter Honored by City & State for Philanthropic Efforts in Support of Feeding America
Dichter named among The Responsible 100 which represents New York s 100 most outstanding corporate citizens
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NEW YORK, Dec. 16, 2020 /PRNewswire/ This evening, Kenny Dichter, Founder and CEO of leading private aviation company Wheels Up, will be honored as one of City & State s Responsible 100 for ongoing philanthropic efforts and initiatives.
Dichter and Wheels Up are being recognized for their support of Feeding America with the March 2020 launch of the Meals Up program, which was created to help raise awareness and funds around the growing levels of food insecurity during the COVID-19 crisis. Meals Up is an extension of Wheels Up Cares, a program that is committed to continually aligning with philanthropic organizations and initiatives that affect and matter to Wheels Up and its members, families