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Targeted radiation is often used to study and treat diverse cancer types. A multidisciplinary research team based at the University of Chicago Medicine has recently focused on a type of cell that releases a protein that enhances resistance to cancer therapies and promotes tumor progression.
The study focused on Ter cells, which are extra medullary erythroid precursers that secrete the neuropeptide artemin. In the study, published February 24, 2020, in
Science Translational Medicine, the researchers showed that local tumor radiotherapy, systemic immunotherapy or the combination of both treatments were able to deplete Ter cells in the spleen, reduce artemin production and limit tumor progression both in the locally irradiated tumors as well as outside the radiation fields.
Study: Depleted uranium from tanks, ammo not tied to Gulf War syndrome bigrapidsnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bigrapidsnews.com Daily Mail and Mail on Sunday newspapers.
Meth has devastated the gay community for decades. A new treatment offers hope. Benjamin Ryan Do you want to be a 50-year-old meth addict?
For Roger, the enormity of what he had lost during his nearly two decades of off-and-on methamphetamine use and what more he had to lose hit home hard when a man he was dating asked him that question.
Roger, who was 47 at the time, had already suffered a major ischemic stroke thanks to meth, the powerfully addictive stimulant that had long since taken over his life.
So when Roger, who is from Dallas and asked that his last name not be published for fear that meth s stigma could hurt his career, heard that a study was looking for people like him to test a treatment for meth use disorder, he jumped at the chance.
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An experimental treatment can essentially reverse type 1 diabetes in certain types of laboratory mice, according to a series of studies led by University of Utah Health scientists. An injection of the therapeutic agent converts cells that normally control glucose production into ones that generate insulin.
The researchers say giving the animals a single dose of a human antibody that suppress the actions of glucagon, a hormone involved in glucose regulation, sparked a remarkable transformation in the pancreas, leading to a nearly 7-fold increase in insulin cell mass and the suppression of diabetic symptoms. These animals go from requiring insulin injections to never requiring a diabetes treatment again. They maintain normal blood glucose long after we stop the treatment, says William L. Holland, Ph.D., the study s corresponding author and a U of U Health assistant professor of Nutrition and Integrative Physiology. What this implies for millions of people who have type