A miniature device the size and shape of an aspirin tablet could provide new options for people with cancer. Developed in the lab of Pinkas Family professor of bioengineering David Mooney, the implantable vaccine, inserted under a patient’s skin, operates like a tiny factory where immune cells of one kind are transformed to train other immune cells to eradicate tumors.
The tablet-like device emits a signal that attracts dendritic cells, the messengers of the immune system, which carry information about the pathogens and toxins they encounter to other immune cells. The dendritic cells “literally crawl inside the plastic device” to be activated by freeze-dried fragments of the patient’s own tumor, Mooney explains. Once the dendritic cells have become activated, they “home to the nearest lymph node,” where they encounter T cells that they train to recognize and destroy cancer cells. The T cells then multiply and circulate through the body, dissolving the patient’s tumor.
Last Comment: December 16, 2020 5:44 am ET | 2 Comment(s) | Jump to Comments
There certainly hasn t been a shortage of win photos for the connections of Major Custard over the past two seasons, but the one from the Saturday (Dec. 12) card at Century Mile could be bittersweet.
Major Custard might have made his final start in Alberta after his co-owner Jim Marino announced that he would be selling a number of his racehorses to concentrate on younger stock. This announcement comes as the province s 2020 harness racing season comes to an end, necessitating a double-header card on Saturday.
Competing in the second of two $22,500 Brad Gunn Breeders Stakes divisions, Major Custard and driver Mike Hennessy sat patiently in fourth during the first half of his contest while Chazmichaelmichael (Kelly Hoerdt) paced through splits of :28.3 and :59.2. Outlaw C My Shadow (Connie Kolthammer) made a move from third just before the half and looped to the lead, leaving Major Custard first up after H