The impact of deploying Artificial Intelligence (AI) for radiation cancer therapy in a real-world clinical setting has been tested by Princess Margaret researchers in a unique study involving physicians and their patients.
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IMAGE: Senior author and Princess Margaret Scientist Dr. Marianne Koritzinsky s research reveals the potential of targeted therapies to exploit unique metabolic features of pancreatic cancer cells. view more
Credit: Visual Services, UHN
(Toronto, Friday, May 7, 2021) Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.
Led by Princess Margaret Cancer Centre (PM) Scientist Dr. Marianne Koritzinsky, researchers showed that about half of patient-derived pancreatic cancer cell lines are highly dependent or addicted to the protein peroxiredoxin 4 (PRDX4), as a result of the altered metabolic state of the cancer cell.
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TORONTO - Scientists at the Krembil Brain Institute, part of University Health Network (UHN), in collaboration with colleagues at the Centre for Addiction and Mental Health (CAMH), have used precious and rare access to live human cortical tissue to identify functionally important features that make human neurons unique.
This experimental work is among the first of its kind on live human neurons and one of the largest studies of the diversity of human cortical pyramidal cells to date. The goal of this study was to understand what makes human brain cells human, and how human neuron circuitry functions as it does, says Dr. Taufik Valiante, neurosurgeon, scientist at the Krembil Brain Institute at UHN and co-senior author on the paper.
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The Winnipeg Regional Health Authorityâs new president and CEO brings more than 30 years of health care operations experience to his new role.
The WHRAâs board of directors announced that Mike Nader will take over leadership of the health authority on May 17.
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Nader has served in executive management roles with public health care systems in British Columbia and Ontario. Most recently, he served as the Chief Transformation Officer at Ontario Health, with responsibility for leading the transition of 20 provincial agencies and local health integration networks into a single provincial agency.