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Researchers partner with industry to create better gene therapy tools A team from the Institute for NanoBioTechnology has streamlined the creation of new viral vectors for delivering gene therapy to patients Credit: Getty Images July 15, 2021 Viruses are experts at infiltrating the body, as the SARS-CoV-2 virus (and resulting COVID-19 pandemic) have amply demonstrated. But their efficiency in targeting specific and isolated cells also make them useful drug delivery vehicles, known as viral vectors. Viral vectors are modified viruses that can act as couriers to transport therapeutic packages to specific diseased cells. These packages contain instructions with modified or designed DNA or RNA to correct or supplement a faulty or missing gene. For instance, the Johnson & Johnson COVID-19 vaccine uses viral vectors to transport modified genetic material from the SARS-CoV-2 virus to cells, generating an immune response.

United kingdomUnited statesHai quan maoSashank reddyNolan sutherlandYining zhuBygina wadaspublishedTranslational tissue engineering centerDepartment of biomedical engineeringAmerican society for geneJohns hopkins technology venturesInstitute for nanobiotechnologyMaterials scienceBiomedical engineeringTranslational tissue engineeringAmerican society