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Nanomedicine targets cardiovascular disease
Michigan State and Stanford researchers have upgraded their Trojan horse therapies designed to fight one of the world’s leading causes of death.
Led by Bryan Smith, an associate professor in MSU’s Department of Biomedical Engineering, the team is building on its nanoscopic tubules that carry drugs to fight atherosclerotic plaques involved in cardiovascular disease.
With the help of some crafty chemistry, the team has enabled the tubes to sense when they’ve successfully entered a cell to release their therapeutic payloads. The team, including first author Yapei Zhang, a postdoctoral fellow in Smith’s lab, published this work online on Nov. 6, 2020, in the journal Nano Research.
by Matt Shipman January 8, 2021 .
RALEIGH – Engineering researchers have developed a new technique for eliminating particularly tough blood clots, using engineered nanodroplets and an ultrasound “drill” to break up the clots from the inside out. The technique has not yet gone through clinical testing. In vitro testing has shown promising results.
Specifically, the new approach is designed to treat retracted blood clots, which form over extended periods of time and are especially dense. These clots are particularly difficult to treat because they are less porous than other clots, making it hard for drugs that dissolve blood clots to penetrate into the clot.
Credit: POSTECH
The COVID-19 pandemic is raising fears of new pathogens such as new viruses or drug-resistant bacteria. To this, a Korean research team has recently drawn attention for developing the technology for removing antibiotic-resistant bacteria by controlling the surface texture of nanomaterials.
A joint research team from POSTECH and UNIST has introduced mixed-FeCo-oxide-based surface-textured nanostructures (MTex) as highly efficient magneto-catalytic platform in the international journal
Nano Letters. The team consisted of professors In Su Lee and Amit Kumar with Dr. Nitee Kumari of POSTECH s Department of Chemistry and Professor Yoon-Kyung Cho and Dr. Sumit Kumar of UNIST s Department of Biomedical Engineering.
Date Time
Nanodroplets and Ultrasound ‘Drills’ Prove Effective at Tackling Tough Blood Clots
Engineering researchers have developed a new technique for eliminating particularly tough blood clots, using engineered nanodroplets and an ultrasound “drill” to break up the clots from the inside out. The technique has not yet gone through clinical testing. In vitro testing has shown promising results.
Specifically, the new approach is designed to treat retracted blood clots, which form over extended periods of time and are especially dense. These clots are particularly difficult to treat because they are less porous than other clots, making it hard for drugs that dissolve blood clots to penetrate into the clot.