Ideas, Inventions And Innovations
COVID-19 Unmasked: Math Model Suggests Optimal Treatment Strategies
A biology-based mathematical model indicates why COVID-19 outcomes vary widely and how therapy can be tailored to match the needs of specific patient groups.
Getting control of COVID-19 will take more than widespread vaccination; it will also require better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.
Credit: CDC/ Alissa Eckert, MS; Dan Higgins, MAMS
To meet this unprecedented challenge, researchers at Massachusetts General Hospital (MGH), in collaboration with investigators from Brigham and Women s Hospital and the University of Cyprus, have created a mathematical model based on biology that incorporates information about the known infectious machinery of SARS-CoV-2, the virus that causes COVID-19, and
Getting control of COVID-19 will take more than widespread vaccination; it will also require better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.
To meet this unprecedented challenge, researchers at Massachusetts General Hospital (MGH), in collaboration with investigators from Brigham and Women’s Hospital and the University of Cyprus, have created a mathematical model based on biology that incorporates information about the known infectious machinery of SARS-CoV-2, the virus that causes COVID-19, and about the potential mechanisms of action of various treatments that have been tested in patients with COVID-19.
Under-recognition of Symptoms May Be Common in Breast Cancer Patients Receiving Radiation
Symptom under-recognition may be more common among younger patients and Black patients
Getty Images
December 14, 2020 Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11. Recognizing side effects is necessary for physicians to provide supportive care to help patients manage their symptoms, said Reshma Jagsi, M.D., D.Phil, the Newman Family Professor and deputy chair of the Department of Radiation Oncology and director of the Center for Bioethics and Social Sciences in Medicine at the University of Michigan.
We Beg to Differ #55 From:
DO WE DARE CALL IT CONSPIRACY?
After a few months, the vaccinations are being propelled forward. There are those- scientists, doctors, investigative journalists- who have spoken out- in articles and in videos. Many of these voices have been removed or censored in social media- all in defense of national and international policies that, like Wall Street, love the vaccination scenario.
Obviously, these censured voices, no matter how credentialed, are conspiracy theorists whose views are competing with governments, giant corporations and Central Banks worldwide. And the claim is that this type of censorship protects human beings lives who need the vaccines, the masks, the social distancing, the quarantines and the lockdowns to keep the pandemic from spreading.
Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema, and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.