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San Diego County Board to Vote on Possibly Waiving Fees for Restaurants

Aryl hydrocarbon receptor suppresses immunity to oral cancer through immune checkpoint regulation

 E-Mail A new Boston University School of Public Health (BUSPH) study has identified for the first time how the aryl hydrocarbon receptor (AhR), an environmental chemical receptor, drives immunosuppression in oral squamous cell carcinoma (OSCC) and that its removal from malignant cells can result in tumor rejection. Published in the journal Proceedings of the National Academy of Sciences, the study findings provide new insight into the biology of cancer immunosuppression, and identify a new target for cancer immunotherapy treatment. Immune checkpoint inhibitors (immunotherapy drugs) are some of the most important treatments that have emerged for treating many cancers, including OSCC. Targeting immune checkpoint molecules such as PD-1, PD-L1 and CTLA4 has demonstrated that immunosuppression plays a significant role in OSCC pathology. But immune checkpoint inhibitors are only effective for about 30 percent of cancer patients, so there is a critical need for researchers to identi

San Diego County considers waiving restaurant fees to offset pandemic losses

Print The county Board of Supervisors will consider waiving restaurant permit fees Wednesday in an effort to help struggling eateries recover from pandemic closures and restrictions. “In the last year, San Diego County restaurants have suffered greatly,” said Supervisor Jim Desmond, who proposed the fee waiver. “We’ve all seen permanently out-of-business signs on many of the favorite restaurants in San Diego County.” With about 8,000 locations employing 126,000 workers, the restaurant sector was hard hit by mandatory closures and health restrictions on indoor dining, Desmond said. Business at San Diego restaurants dropped by 60 to 77 percent during the pandemic closures in April 2020 and remained below pre-pandemic levels as of January, according to a board of supervisors letter, citing figures from the San Diego Association of Governments.

Tracking Israeli Involvement: University of North Carolina generated COVID-19 (censored/suppressed) – Veterans Today | Military Foreign Affairs Policy Journal for Clandestine Services

Tracking Israeli Involvement: University of North Carolina generated COVID-19 (censored/suppressed) – Veterans Today | Military Foreign Affairs Policy Journal for Clandestine Services
veteranstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from veteranstoday.com Daily Mail and Mail on Sunday newspapers.

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