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Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases Apr 5 2021 A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death. Stephen S. Rich, PhD, a genetics researcher at the School of Medicine, helped lead a massive genome analysis of more than 53,000 people. Image Credit: UVA Health The analysis from the Trans-Omics for Precision Medicine (TOPMed) program examines the complete genomes of 53,831 people of diverse backgrounds on different continents. Most are from minority groups, which have been historically underrepresented in genetic studies. The increased representation should translate into better understanding of how heart, lung, blood and sleep disorders affect minorities and should help reduce longstanding health disparities.

Joe mychaleckyjSchool of medicineNational institutes of health heartSteering committeePublic health genomicsUniversity of virginiaDepartment of public health sciencesBlood institutePrecision medicineGenetics researcherProject leadExecutive committeeAakrosh ratanPublic healthNational institutesNational heart