Page 2 - துறை ஆஃப் மருத்துவ நுண்ணுயிரியல் நோயெதிர்ப்பு News Today : Breaking News, Live Updates & Top Stories | Vimarsana

 E-Mail IMAGE: Mutagenesis Model of Molnupiravir. SARS-CoV-2 polymerase (oval) mediated nucleotide incorporation into the RNA primer (grey circles)/template (white circles). Plus and minus sense indicate RNA sense. A, C, G, and U. view more  Credit: Supplied by Matthias Gotte A University of Alberta virology lab has uncovered how an oral antiviral drug works to attack the SARS-CoV-2 virus, in findings published May 10 in the Journal of Biological Chemistry. The researchers demonstrated the underlying mechanism of action by which the antiviral drug molnupiravir changes the viral genome, a process known as excessive mutagenesis or error catastrophe. The polymerase, or replication engine of the virus, mistakes molnupiravir molecules for the natural building blocks required for viral genome replication and mixes them in, explained Matthias Götte, professor and chair of the Department of Medical Microbiology & Immunology in the Faculty of Medicine & Dentistry and

United statesRidgeback biotherapeuticsRaymond schinaziEgor tchesnokovCalvin gordonA university of albertaWorld health organizationAlberta ministry of jobsLi ka shing institute of virologyCanadian institutes of health researchDepartment of medical microbiology immunologyEmory school of medicineEmory university in atlantaUs national institutes of health centersMedical microbiologyEmory university