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New technique identifies specific neural pathways involved in executive functions of the brain

New technique identifies specific neural pathways involved in executive functions of the brain The human brain is a wonderfully enigmatic organ, helping to juggle multiple tasks efficiently to help us get through a long day! This feature, called executive function, seats primates like us at the pinnacle of evolution. The prospect of losing the spectacular flow of neural information in our brains because of an accident or disease is, thus, unnerving. In the event of such an unfortunate occurrence, to restore the brain to its previous working condition with full functionality to reboot it, so to speak would need a better understanding of the specific neural pathways involved in our daily activities that rely on working memory and decision-making two important executive functions.

Takafumi minamimotoKei oyamaEmily hendersonNational institutes for quantumDepartment of functional brain imagingNational institutesRadiological scienceScience advancesFunctional brain imagingStudy firstஎமிலி ஹென்டர்சன்தேசிய நிறுவனங்கள் க்கு குவாண்டம்தேசிய நிறுவனங்கள்கதிரியக்கவியல் அறிவியல்செயல்பாட்டு மூளை இமேஜிங்படிப்பு முதல்

New PET imaging method tracks immunotherapeutic efficacy in mouse models

New PET imaging method tracks immunotherapeutic efficacy in mouse models Several cancer tumors grow through immunosuppression; that is, they manipulate biological systems in their microenvironments and signal to a specific set of immune cells those that clear out aberrant cells to stop acting. It is no wonder that immunotherapy designed to re-establish anti-tumor immunity is rapidly becoming the treatment of choice for these cancers. One natural immunosuppressive molecule that falls prey to helping cancer tumors is indoleamine-2,3-dioxygenase 1 (henceforth, IDO1). Because it is found in a broad range of cancer tumors, including those of the skin, breast, colon, lung, and blood, scientists have begun to see it as a promising therapeutic target: Suppress its activity and anti-tumor immunity should be back. But all endeavors so far have failed in phase 3 clinical trials the stage at which a large number of people with the disease try out the optimal dose to test its true efficacy.

Ming rong zhangLin xieEmily hendersonNational institutes for quantumDepartment of advanced nuclear medicine sciencesAdvanced nuclear medicine sciencesNational institutesRadiological scienceலின் க்ஷிஎஎமிலி ஹென்டர்சன்தேசிய நிறுவனங்கள் க்கு குவாண்டம்தேசிய நிறுவனங்கள்கதிரியக்கவியல் அறிவியல்

Novel technique decodes mechanisms controlling executive functions of the primate brain

Novel technique decodes mechanisms controlling executive functions of the primate brain
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Takafumi minamimotoYuji nagaiNaohisa miyakawaKei oyamaMakoto higuchiMasahiko takadaKoki mimuraToshiyuki hirabayashiTetsuya suharaCircuits research groupNational institutes for quantumStrategic grant creative researchKyoto universityResearch articleNational bioDepartment of functional brain imaging

Novel technique decodes mechanisms controlling executive functions of primate brain

The National Institutes for Quantum and Radiological Science and Technology The human brain is a wonderfully enigmatic organ, helping to juggle multiple tasks efficiently to help us get through a long day! This feature, called executive function, seats primates like us at the pinnacle of evolution. The prospect of losing the spectacular flow of neural information in our brains because of an accident or disease is, thus, unnerving. In the event of such an unfortunate occurrence, to restore the brain to its previous working condition with full functionality–to reboot it, so to speak–would need a better understanding of the specific neural pathways involved in our daily activities that rely on working memory and decision-making–two important executive functions.

Takafumi minamimotoKei oyamaNational institutes for quantumDepartment of functional brain imagingNational institutesRadiological scienceScience advancesFunctional brain imagingதேசிய நிறுவனங்கள் க்கு குவாண்டம்தேசிய நிறுவனங்கள்கதிரியக்கவியல் அறிவியல்செயல்பாட்டு மூளை இமேஜிங்

Neural Mechanism Behind Executive Function is Found by a Novel Technique

Neural Mechanism Behind Executive Function is Found by a Novel Technique
medindia.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medindia.net Daily Mail and Mail on Sunday newspapers.

National institutes for quantumNational institutesRadiological scienceதேசிய நிறுவனங்கள் க்கு குவாண்டம்தேசிய நிறுவனங்கள்கதிரியக்கவியல் அறிவியல்