Researchers investigate antibodies that best neutralize SARS-CoV-2 in COVID-19 patients
The COVID-19 pandemic has now claimed over 2 million deaths worldwide, and this number is only increasing. In response, health agencies have rolled out tests to diagnose and understand the disease.
Besides the now widely known PCR test, there is interest in serological (blood) tests that detect antibodies against SARS-CoV-2, the virus that causes COVID-19. These blood tests have considerable applications, from identifying blood donors with high levels of anti-SARS-CoV-2 antibodies, whose blood can be used for convalescent plasma therapy, to measuring vaccine effectiveness.
So, what are antibodies? These are proteins produced by the body s immune system to combat foreign proteins, such as the SARS-CoV-2 virus. Antibodies function by binding to a specific part of the virus that the immune system recognizes, called antigens. SARS-CoV-2 is composed of four major proteins, with two being highly
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