NIH awards $3.1 million grant for Washington University, St. Jude ALS research
Five-year grant to McKelvey School of Engineering’s Pappu and co-PI Mittag will support study of RNA-binding proteins
March 5, 2021 SHARE Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering, received funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS).
Scientists from Washington University in St. Louis and St. Jude Children’s Research Hospital have been awarded a five-year $3.1 million grant from the National Institute of Neurological Disorders and Stroke, an affiliate of the National Institutes of Health (NIH).
Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering, received funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS).
Scientists from Washington University in St. Louis and St. Jude Children’s Research Hospital have been awarded a five-year $3.1 million grant from the National Institute of Neurological Disorders and Stroke, an affiliate of the National Institutes of Health (NIH).
Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering in the McKelvey School of Engineering at Washington University, and Tanja Mittag, of the St. Jude Department of Structural Biology, received the funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.
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MINNEAPOLIS, March 5, 2021 /PRNewswire/ Children born to women taking certain medications for epilepsy during pregnancy have no developmental delays at age three when compared to children of healthy women without epilepsy, according to a preliminary study released March 4, 2021, that will be presented at the American Academy of Neurology s 73
rd Annual Meeting being held virtually April 17 to 22, 2021. Most of the women with epilepsy in the study took either lamotrigine or levetiracetam during their pregnancy, or a combination of the two. Having a seizure during pregnancy may not only harm the mother but possibly the baby as well, so seizure control is an important part of prenatal care, said study author Kimford J. Meador, M.D., of Stanford University in Stanford, Calif., and a Fellow of the American Academy of Neurology. Yet, antiseizure drugs are known to cause birth defects or neurobehavioral problems, but these effects vary widely
Credit: Courtesy of the Lundbeck Foundation, Denmark.
WHAT:
The Brain Prize has been awarded to Michael A. Moskowitz, M.D., a professor of neurology at Harvard Medical School at the Massachusetts General Hospital, Charlestown, who also is supported by an NIH grant. The Brain Prize is the world s most prestigious award for brain research and is awarded by the Lundbeck Foundation, Denmark. Dr. Moskowitz will receive the prize along with three other scientists for their pathbreaking contributions that led to novel migraine therapies.
The Lundbeck Foundation said, Moskowitz showed in experimental models that a migraine attack is triggered when trigeminal nerve fibres release neuropeptides that lead to dilated (opened up) blood vessels of the meninges, inflammation, and pain.. He was the first to propose that blocking the action of released neuropeptides could be a new approach to treating migraine.