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VIDEO: Researchers at the University of Minnesota College of Science and Engineering used a unique mini-microscope device to image complex brain activity of mice that show multiple areas of the brain. view more
Credit: Rynes and Surinach, et al., Kodandaramaiah Lab, University of Minnesota
Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.
The device, known as the mini-MScope, offers an important new tool for studying how neural activity from multiple regions of the outer part of the brain, called the cortex, contribute to behavior, cognition and perception. The groundbreaking study provides new insight into fundamental research that could improve human brain conditions such as concussions, autism, Alzheimer s, and Pa
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Philadelphia, March 17, 2021 - Researchers from Children s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism. By linking clinical features to genetic abnormalities in a standardized format, the researchers hope their findings lead to improved identification and clinical intervention.
The study was published online by the journal
Genetics in Medicine.
Pathogenic variants in the SCN2A gene can lead to a wide range of clinical features - or phenotypes - associated with neurodevelopmental disorders. Several studies have described the genetic information collected on individuals with disease-causing changes in this gene. However, while genetic information is collected in a standardized manner, data on phenotypes is not
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Researchers Provide Complete Clinical Landscape for Major Gene Linked to Epilepsy and Autism
Researchers from Children’s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism. By linking clinical features to genetic abnormalities in a standardized format, the researchers hope their findings lead to improved identification and clinical intervention.
The study was published online by the journal Genetics in Medicine.
Pathogenic variants in the SCN2A gene can lead to a wide range of clinical features – or phenotypes – associated with neurodevelopmental disorders. Several studies have described the genetic information collected on individuals with disease-causing changes in this gene. However, while genetic informat
Nanotechnology Now
Home > Press > Bioinformatics tool accurately tracks synthetic: DNA Computer scientists show benefits of bioinformatics with PlasmidHawk
The Rice University computer science lab of Todd Treangen challenged and beat deep learning in a test to see if a new bioinformatics approach effectively tracks the lab of origin of a synthetic genetic sequence.
CREDIT
Tommy LaVergne/Rice University
Abstract:
Tracking the origin of synthetic genetic code has never been simple, but it can be done through bioinformatic or, increasingly, deep learning computational approaches.
Bioinformatics tool accurately tracks synthetic: DNA Computer scientists show benefits of bioinformatics with PlasmidHawk
Houston, TX | Posted on February 26th, 2021