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Two children with lung cancer in Japan acquired the tumour cells from their mothers during or shortly before birth – an incredibly rare way of developing the disease.
Chitose Ogawa at the National Cancer Center Hospital in Tokyo and her colleagues made the discovery while sequencing the DNA of the children’s tumours for a prospective clinical trial.
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The first boy was diagnosed with lung cancer at 23 months old, while the second boy was 6 years old when he developed chest pain, leading doctors to discover a tumour in his left lung.
Both mothers turned out to have cervical cancer: the mother of the first boy was diagnosed three months after the birth and the mother of the second boy was diagnosed following delivery.
Can Infants Catch Cancer from their Mothers at Birth? Published January 7th, 2021 - 12:02 GMT
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In extremely rare instances, newborns can contract cancer from their pregnant moms during delivery, a new case report suggests.
Two boys, a 23-month-old and a 6-year-old, developed lung cancers that proved an exact genetic match to cervical cancers within their mothers at the time of birth, Japanese researchers report.
It appears that the boys breathed in cancer cells from their mothers tumors while they were being born, cancer experts say. In our cases, we think that tumors arose from mother-to-infant vaginal transmission through aspiration of tumor-contaminated vaginal fluids during birth, said lead researcher Dr. Ayumu Arakawa, a pediatric oncologist with the National Cancer Center Hospital in Tokyo.
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