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Is a Waning Locus Coeruleus an Early Sign of Alzheimer s Disease?
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Assessing the Link Between Alzheimer Disease Co-Pathology and Neuropsychiatric Symptoms in Lewy Body Dementia
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The Brain s Blue Spot May Help Identify Alzheimer s Earlier
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A history of either anxiety or depression was inversely associated with the age when Alzheimer s disease started, a retrospective analysis suggested.
People with Alzheimer s disease who had a past diagnosis of anxiety were 3 years younger than other Alzheimer s patients when they developed the disease, reported Zachary Miller, MD, of the University of California San Francisco (UCSF), and co-authors.
Patients with a history of depression were 2 years younger at Alzheimer s onset, they said in an abstract released in advance of the 2021 American Academy of Neurology annual meeting.
The findings were based on 1,500 Alzheimer s disease patients from the UCSF Memory and Aging Center who were screened for past psychiatric disorders, including depression, anxiety, bipolar disorder, schizophrenia, and post-traumatic stress disorder (PTSD). Researchers evaluated typical Alzheimer s risk factors hypertension, hyperlipidemia, diabetes, education, and
Ofer Harel, Ph.D. is a professor and Director of admission in the Department of Statistics and a (past) principal Investigator in the Institute for Collaboration on Health, Intervention, and Policy (InCHIP) at the University of Connecticut. Dr. Harel received his doctorate in statistics in 2003 from the Pennsylvania State University; where he developed his methodological expertise in the areas of missing data techniques, diagnostic tests, longitudinal studies, Bayesian methods, sampling techniques, mixture models, latent class analysis, and statistical consulting. Dr. Harel received his post-doctoral training at the University of Washington, Department of Biostatistics, where he worked for the Health Services Research & Development (HSR&D) Center of Excellence, VA Puget Sound Healthcare System, and the National Alzheimer’s Coordinating Center (NACC). Dr. Harel has served as a biostatistical consultant nationally and internationally since 1997. Through his collaborative consulting,