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IMAGE: Yap hadal snailfish (YHS) in situ at 6,903 m (above) and after capture (below). view more
Credit: Mu Y et al., 2021, PLOS Genetics
A new whole genome sequence for the Yap hadal snailfish provides insights into how the unusual fish survives in some of the deepest parts of the ocean. Xinhua Chen of the Fujian Agriculture and Forestry University and Qiong Shi of the BGI Academy of Marine Sciences published their analysis of the new genome May 13th in the journal
PLOS Genetics.
Animals living in deep-sea environments face many challenges, including high pressures, low temperatures, little food and almost no light. Fish are the only animals with a backbone that live in the hadal zone defined as depths below 6,000 meters and hadal snailfishes live in at least five separate marine trenches. Chen, Shi and their colleagues constructed a high-quality whole genome sequence from the Yap hadal snailfish to understand how it has adapted to life in the deep sea. The
Chinese Academy of Sciences
Recently, the research group led by Prof. YU Ziniu from the South China Sea Institute of Oceanology (SCSIO) of the Chinese Academy of Sciences sequenced the first complete Natuilus genome and unveiled the evolutionary features underlying the pinhole eye formation and biomineralization.
This study was published in Nature Ecology & Evolution on May 10.
Nautilus is the only surviving externally shelled cephalopod since the Palaeozoic. They have preserved many ancestral features despite a long evolutionary history, such as a chambered shell and pinhole eye.
The researchers sequenced the complete genome of N. pompilius, which is the most widespread species among nautiluses. The genome was 730.58 (Mb) in size and encoded 17,170 protein-coding genes, presenting a most compact, simple and slow-evolving genome when compared to other coleoid cephalopods.
A high-tech textile to stay comfortable outdoors - American Chemical Society acs.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from acs.org Daily Mail and Mail on Sunday newspapers.
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IMAGE: Thermal imaging shows how a square of the new textile (dashed lines) traps heat in heating mode (top), while reflecting it in cooling mode (bottom). view more
Credit: Adapted from
2021, DOI: 10.1021/acs.nanolett.1c00400
Clothing, from tank tops to parkas, helps people adapt to temperatures outdoors. But you can only put on or take off so much of it, and fluctuations in weather can render what you are wearing entirely inadequate. In a new study in ACS
Nano Letters, researchers describe a high-tech alternative: a reversible textile they designed to trap warmth in the cold and reflect it during hot weather, all while generating small amounts of electricity.
Cd86), were down-regulated in
Mettl3-deficient cells (Fig. 1G), suggesting that METTL3 has a critical function in controlling the innate immune response of Raw 264.7 macrophages.
To further confirm the biological role of the m
6A modification in macrophages,
Mettl3 conditional KO (CKO) mice were generated by crossing
Mettl3
flox/flox mice with mice expressing Cre recombinase under the control of lysozyme 2 promoter (
Lyzm-Cre). We have documented the loss of both the METTL3 protein and the overall m
6A modification in bone marrow–derived macrophages (BMDMs) from
Mettl3
flox/flox;
Lyzm-Cre mice (fig. S1I). No differences in the frequency of major immune cell populations were observed between