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29 and correlated with progression and poor prognosis of glioma patients. It also reported that LSH associated with the HOX gene families, which regulating DNA methylation and HOX gene silencing during development. In the present study, the expression of HOXC11 and LSH in 84 clinical samples and samples from two databases, The Cancer Genome Atlas database and Kaplan-Meier plotter gastric cancer datasets, were analyzed, as well as the relationship between HOXC11 and LSH expression and clinicopathological features and survival times. After that, HOXC11 and LSH were over-expressed in MKN-45 gastric signet ring cell carcinoma cell line for cell proliferation, migration, cell cycle, and apoptosis assays.

United statesAssociation betweenAmerican joint committee on cancerSangon biotech corporationUnion for international cancerDepartment of pathology xiangya hospitalL sangon biotech corporationL rnase sangon biotech corporationZhongshan jinqiao corporationCancer research institute of central south universityGlobal cancer observatoryCancer genome atlasXiangya hospitalAmerican joint committeeInternational cancer controlCancer research institute