New method of producing drug candidates may lead to better medicines in the future
A lot of our medicines and other bioactive drugs are based on chemical structures called enantiomers molecules that are mirror images of each other and are non-superimposable. Notable among them are chiral N,N-acetals contained in diuretic drugs like bendroflumethiazide and thiabutazide, used to treat high blood pressure and edema.
Because an enantiomer and its mirror image version often have different biological activities, with only one of them having pharmacological utility, an enantioselective or asymmetric synthesis yielding the desired enantiomer in greater amounts is highly desirable.
E-Mail
IMAGE: A possible mechanism for the formation of chiral N,N-acetal via reaction between 2-aminobenzamide and α-ketoester in presence of chiral bis(imidazoline)-phosphoric acid catalyst view more
Credit: Picture courtesy: Shuichi Nakamura from NITech
A lot of our medicines and other bioactive drugs are based on chemical structures called enantiomers molecules that are mirror images of each other and are non-superimposable. Notable among them are chiral N,N-acetals contained in diuretic drugs like bendroflumethiazide and thiabutazide, used to treat high blood pressure and edema. Because an enantiomer and its mirror image version often have different biological activities, with only one of them having pharmacological utility, an enantioselective or asymmetric synthesis yielding the desired enantiomer in greater amounts is highly desirable.
碳化硅（SiC) 迎来爆发！_露笑科技(002617)股吧_东方财富网股吧 eastmoney.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eastmoney.com Daily Mail and Mail on Sunday newspapers.
How crystal defects can help convert waste heat into electricity
How crystal defects in Ni-based alloys give rise to high thermoelectric conversion efficiencies, advancing thermoelectric technology
Photo courtesy: Hidetoshi Miyazaki from Nagoya Institute of Technology
Examples of applications of power generation using thermoelectric conversion. It involves conversion of exhaust heat from automobile engines into electricity for reuse, or using the difference in temperature between the human body and ambient air to generate electricity that can power IoT sensors. Zoom in ).addClass( image-details ); var $imageCaption = $( ).addClass( image-caption ).text(caption); $imageDetails.append($imageCaption); element = $( ).append( × ).append($imageHolder).append($imageDetails)[0]; img.draggable = false;
E-Mail
IMAGE: Examples of applications of power generation using thermoelectric conversion. It involves conversion of exhaust heat from automobile engines into electricity for reuse, or using the difference in temperature between the. view more
Credit: Photo courtesy: Hidetoshi Miyazaki from Nagoya Institute of Technology
If we are to prevent the impending environmental crisis, it is imperative that we find efficient and sustainable ways to avoid being wasteful. One area with much room for improvement is the recycling of waste heat from industrial processes and technological devices into electricity. Thermoelectric materials are at the core of research in this field because they allow for clean power generation at little cost.