13 also exhibited high antiviral activity against SARS-CoV-2, the virus that causes COVID-19.
Figure 1. (a) Antiviral activity of prepared powders against coronavirus and photographs showing the change in plaque number of coronavirus after four hours: (b) control and (c) with CMO.
After four hours, the CMO powder reduced the level of coronavirus by four orders of magnitude (to less than 1/10,000 of the original level). The antiviral activity of CMO against coronavirus was found to exceed that of both LCMO and MoO
3.
The researchers infer that an effective combination of cerium with the molybdate ion as well as the specific surface area
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IMAGE: (a) Antiviral activity of prepared powders against coronavirus and photographs showing the change in plaque number of coronavirus after four hours: (b) control and (c) with CMO. view more
Credit: Material letters
Researchers at Tokyo Institute of Technology working in collaboration with colleagues at the Kanagawa Institute of Industrial Science and Technology and Nara Medical University in Japan have succeeded in preparing a material called cerium molybdate (γ-Ce2Mo3O13 or CMO), which exhibits high antiviral activity against coronavirus.
The ongoing coronavirus pandemic has highlighted the urgency not only of vaccine development and rollout but also of developing innovative materials and technologies with antiviral properties that could play a vital role in helping to contain the spread of the virus.
TOYOHASHI, Aichi Prefecture A start-up company here developed equipment that uses ozone gas to blow away and suck in viruses from people and their clothes.
The device resembles stand-up scanners used at airports to screen passengers for items or contraband they are prohibited from taking on to aircraft.
The company, o3peace, says the product ensures that anybody with the novel coronavirus attached to the body surface and clothes will get a clean pass before entering a building.
It is hoping to sell its gate-shaped ozone gas sprayer to hotels and other commercial facilities.
“Ozone is widely used for sterilization and tap water purification in Germany and elsewhere,” noted Yoshiyuki Hagiwara, 42, founder and president of o3peace. “Our goal in future is for large airports to adopt the product.”
Researchers use cachexia model to assess cancer-derived myocardial impairments
Oncotarget recently published Evaluation of cancer-derived myocardial impairments using a mouse model which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder.
Using the mouse cachexia model that they established previously, the authors investigated myocardial damage in tumor-bearing mice.
When rat cardiomyoblasts were treated with mouse cachexia model ascites and subjected to flux analysis, both oxidative phosphorylation and glycolysis were suppressed, and the cells were in a quiescent state.
These results are in good agreement with those previously reported on cancerous myocardial damage.
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IMAGE: Energy metabolism in the myocardium of CT26-inoculated BALB/c mice. (A) Protein levels of HMGB1 and TNFα in the ascites of CT26-inoculated BALB/c mice or H9c2 cultured medium (CM). (B) Cell. view more
Credit: Correspondence to - Yi Luo - lynantong@hotmail.com and Hiroki Kuniyasu - cooninh@zb4.so-net.ne.jp
Evaluation of cancer-derived myocardial impairments using a mouse model which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder.
Using the mouse cachexia model that they established previously, the authors investigated myocardial damage in tumor-bearing mice.