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KEYTRUDA (pembrolizumab) Plus LENVIMA (lenvatinib) Demonstrated Superior Progression-Free Survival (PFS) and Overall Survival (OS) Versus Sunitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma

KEYTRUDA (pembrolizumab) Plus LENVIMA (lenvatinib) Demonstrated Superior Progression-Free Survival (PFS) and Overall Survival (OS) Versus Sunitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma
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KEYTRUDA® Plus LENVIMA® Demonstrated Superior Progression-Free Survival and Overall Survival Versus Sunitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma

KEYTRUDA Plus LENVIMA Significantly Reduced Risk of Disease Progression or Death by 61% Versus Sunitinib, With a Median PFS of Nearly Two Years Versus Nine Months for Sunitinib LENVIMA Plus Everolimus Significantly Improved PFS and Objective Response Rate Versus Sunitinib First Results From Pivotal CLEAR Study Presented at 2021 Genitourinary Cancers Symposium and Published in the New England Journal of Medicine … KEYTRUDA Plus LENVIMA Significantly Reduced Risk of Disease Progression or Death by 61% Versus Sunitinib, With a Median PFS of Nearly Two Years Versus Nine Months for Sunitinib LENVIMA Plus Everolimus Significantly Improved PFS and Objective Response Rate Versus Sunitinib First Results From Pivotal CLEAR Study (KEYNOTE-581/Study 307) Presented at 2021 Genitourinary Cancers Symposium (ASCO GU) and Published in the New England Journal of Medicine

Study reveals mutations that drive therapy-related myeloid neoplasms in children

 E-Mail IMAGE: Xiaotu Ma, Ph.D., St. Jude Computational Biology, and Jeffery Klco, M.D., Ph.D., St. Jude Pathology view more  Credit: St. Jude Children s Research Hospital Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis. Scientists at St. Jude Children s Research Hospital have characterized the genomic abnormalities of 84 such myeloid neoplasms, with potential implications for early interventions to stop the disease. A paper detailing the work was published today in Nature Communications. The somatic (cancer) and germline (inherited) genomic alterations that drive therapy-related myeloid neoplasms in children have not been comprehensively described, until now. The researchers used a variety of sequencing techniques (whole exome, whole genome and RNA) to characterize the genomic profile of 84 pediatric therapy-related myeloid neoplasms. The data came from

Antibody Tests Can t Measure COVID-19 Immunity

The Atlantic Antibody tests for the coronavirus have just one scientifically sanctioned job in the clinic. Designed to detect a delayed immune response to the virus, they can help patients determine whether they were once infected effectively, a retroactive diagnosis. That’s not how a lot of antibody tests are being used. Across the country, people have flocked to test sites to determine whether they are “immune” to the coronavirus, or even to obtain results that could green-light them to board an international flight. Now they are taking these tests to check whether the vaccine they received actually took. Some experts are even debating whether the tests could serve as a screening tool to identify candidates who might be eligible to skip their second COVID-19 shot.

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