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 E-Mail 2+ ion flux and immune responses view more  Credit: BI et al., Cell In plants, disease resistance proteins serve as major immune receptors that sense pathogens and pests and trigger robust defense responses. Scientists previously found that one such disease resistance protein, ZAR1, is transformed into a highly ordered protein complex called a resistosome upon detection of invading pathogens, providing the first clue as to how plant disease resistance proteins work. Precisely how a resistosome activates plant defenses, however, has been unclear. A joint team led by Profs. ZHOU Jianmin, CHEN Yuhang and HE Kangmin at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences and Prof. CHAI Jijie at Tsinghua University recently employed state-of-the-art electrophysiology and single-molecule imaging to investigate the molecular mechanism by which the ZAR1 resistosome activates plant immunity.

National natural science foundation of chinaNational key researchInstitute of geneticsDevelopment program of chinaJijie at tsinghua universityDevelopmental biologyChinese academyTsinghua universityNational natural science foundationDevelopment programதேசிய இயற்கை அறிவியல் அடித்தளம் ஆஃப் சீனாதேசிய விசை ஆராய்ச்சிநிறுவனம் ஆஃப் ஜெநெடிக்ஸ்வளர்ச்சி ப்ரோக்ர்யாம் ஆஃப் சீனாவளர்ச்சி உயிரியல்சீன கலைக்கழகம்