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New study can help determine effectiveness of chemotherapy in patients with bladder cancer In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body s immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charité - Universitätsmedizin Berlin and the Berlin Institute of Health. The findings, which have been published in Science Translational Medicine, can be used to predict treatment success and may increase survival in patients with bladder cancer. Bladder cancer is one of the ten most common types of cancer in Germany, and one of the five most common cancers in men. Nationwide, the disease affects approximately 30,000 people a year. The risk of cancer spreading (metastasizing) is particularly high once it invades the muscle layer inside the bladder wall.

Tino vollmerMichael schmEmily hendersonSamir sherifBerlin institute of health centerInstitute of medical immunologyBerlin centerBerlin institute of healthBerlin instituteScience translational medicineHealth centerRegenerative therapiesMedical immunologyAdvanced therapiesCancer genomeBladder cancer