First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer s disease news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
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IMAGE: Mireia Seuma (left), first author of the study and researcher at IBEC next to Benedetta Bolognesi (right), one of the lead authors of the study and Junior Group Leader at. view more
Credit: The Institute for Bioengineering of Catalonia, IBEC
A study published in the journal
eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer s disease.
The comprehensive mutation map, which is the first of its kind, has the potential to help clinical geneticists predict whether the mutations found in amyloid beta can make an individual more prone to developing Alzheimer s disease later in life.
2nd March 2021 11:23 am 2nd March 2021 11:23 am
An international project aims to create new photonic tools that can access the deep brain and provide further understanding of neurological diseases.
Image by Colin Behrens from Pixabay
Strathclyde University is the UK participant in DEEPER (Deep Brain Photonic Tools for Cell-Type Specific Targeting of Neural Diseases), which is investigating the deep-brain alterations underlying the origin of neurological and psychiatric diseases such as dementia, depression, addiction, schizophrenia and chronic pain.
The four-year study involves 12 partners in eight countries, coordinated by Italian Institute of Technology (IIT), and has received funding of approximately €5.7m from the European Union via the Horizon 2020 programme.
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Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this reality had been identified in the brain of mice, their existence in our species had not been corroborated.
Now, an international group of researchers led by ICREA Research Professor Paul Verschure from the SPECS laboratory at the Institute for Bioengineering of Catalonia (IBEC) and Professor Nikolai Axmacher from the Department of Neuropsychology at Ruhr-Universität Bochum (Germany), in collaboration with Pompeu Fabra University and Dr. Rodrigo Rocamora from Hospital del Mar, have identified for the first time in humans, the mechanism responsible for this phenomenon.
International Consortium to Develop Photonic Tools for Deep Brain Imaging | Business | Jan 2021 photonics.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from photonics.com Daily Mail and Mail on Sunday newspapers.