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Early-life Trauma Affects MS Development, Treatment in Mice 4.8 (30) Childhood trauma can affect disease progression of multiple sclerosis (MS) and treatment in adulthood, a study in mice suggests. The study shows that mice that experienced early-life trauma were more likely to develop an autoimmune condition and less likely to respond to common treatment with interferon beta. The study, “ MS is a progressive, multifactorial disease with both genetic and environmental factors contributing to it. Childhood trauma (early-life) trauma emotional neglect or physical abuse, for instance has been associated with higher relapse rates in MS. However, the underlying mechanism through which it alters MS progression remains unknown.

Yee ming khawMakoto inoueNature communicationsLeiden university medical centerBiomedical sciencesUniversity of illinois urbana champaignIllinois urbana champaignMing khawUniversidade nova de lisboaMedical microbiologyInfectious diseasesApplied biologyInstituto de medicina molecularமெகோடோ இணௌஊேஇயற்கை தகவல்தொடர்புகள்உயிர் மருத்துவ அறிவியல்