Study Shows How Poor Oral Hygiene may Result in Metabolic Syndrome by Colleen Fleiss on December 13, 2020 at 10:55 PM
A new mechanism by which periodontal disease may cause diabetes has been discovered by Tokyo Medical and Dental University (TMDU) researchers.
In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered that infection with Porphyromonas gingivalis, the bacterium causing periodontal disease, causes skeletal muscle metabolic dysfunction, the precursor to metabolic syndrome, by altering the composition of the gut microbiome.
Periodontal bacteria have long been known to cause inflammation within the oral cavity, but also systemically increase inflammatory mediators. As a result, sustained infection with periodontal bacteria can lead to increases in body weight and lead to increased insulin resistance, a hallmark of type 2 diabetes.
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