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New Treatment Holds Potential to Prevent Crohn s Disease

New Treatment Holds Potential to Prevent Crohn s Disease by Angela Mohan on  December 23, 2020 at 11:27 AM New treatment for Crohn s demonstrated in a mouse model using immune-reactive T cells found to prevent Crohn s disease. This research, led by University of Alabama at Birmingham researcher Charles O. Elson, M.D., professor of medicine, focused on a subset of T cells known as T memory, or Tm cells. The UAB researchers used a triple-punch treatment to remove Tm cells and increase the number of T regulatory, or Treg, cells. Both of these results were able to prevent colitis in a T cell transfer mouse model, and they had similar inhibitory effects on immune-reactive CD4-positive T cells isolated from Crohn s disease patient blood samples.

A safe holiday connection

This holiday gathering safely allowed some UAB patients with vision impairment to visit with their friends and colleagues. The staff of UAB Connections, a support group for adults with a vision impairment and their families, held a drive-by holiday celebration for their participants this weekend. The socially distanced event was a chance for members of the support group to visit and chat with each other and their caregivers. “We hadn’t been able to hold an in-person event since February due to the pandemic, so this was a perfect opportunity for old friends to catch up,” said Laura Dreer, Ph.D., an associate professor of ophthalmology at the University of Alabama at Birmingham and director of Connections. “Everyone said it was a wonderful change from their usual life during COVID, which is pretty much just going to doctors’ offices, getting medications, adult children urging them not to go out and do things so they don’t get infected, and basically just sitting at

Hospitals face shortage of nurses, doctors

COVID-19 cases continue to climb Medical personnel tend to a COVID-19 patient at Providence Holy Cross Medical Center in Los Angeles in November. California is desperately searching for nurses, doctors and other medical staff, perhaps from overseas, to meet demands. (Associated Press) A woman holds the hand of her husband in his final moments in a COVID-19 unit at St. Jude Medical Center in Fullerton, Calif., earlier this year. (Associated Press) / Associated Press With so many states seeing a flood of coronavirus patients, hospitals again are worried about finding enough medical workers to meet demand just as infections from the holiday season threaten to add to the burden on American health care.

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