High individual-level variability in SARS-CoV-2 shedding may explain superspreading
Researchers in the United States have provided a high-resolution description of the viral dynamics involved in acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).
The team’s daily longitudinal sampling of 60 newly infected individuals revealed that significant person-to-person variation in the shedding of infectious virus contributes to superspreading.
Superspreading is the term used to describe a small fraction of infected individuals accounting for a disproportionate level of community transmission.
“These results provide the first high-resolution, multi-parameter empirical profile of acute SARS-CoV-2 infection in humans and implicate person-to-person variation in infectious virus shedding in driving patterns of epidemiological spread of the pandemic,” writes Christopher Brooke from the University
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